C4A Antibody / Complement C4A

Western blot: 1:500-1:2000

Optimal dilution of the C4A antibody should be determined by the researcher.

This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. [RefSeq]

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide specific to human C4A / Complement C4A was used as the immunogen for the C4A antibody.

This C4A antibody is available for research use only.

Affinity purified

Human

P0C0L4