NSJ Bioreagents

Arachidonate 5-Lipoxygenase Antibody / ALOX5

Product Code:
 
NSJ-RQ5292
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
AECE-1
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store the 5-Lipoxygenase antibody at -20°C.
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Western blot testing of human K562 cell lysate with 5-Lipoxygenase antibody. Predicted molecular weight ~78 kDa.
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Western blot testing of human K562 cell lysate with 5-Lipoxygenase antibody. Predicted molecular weight ~78 kDa.

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NSJ-RQ5292-100ul100ul£535.00
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Further Information

Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the 5-Lipoxygenase antibody should be determined by the researcher.
Description:
The ALOX5 gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human 5-Lipoxygenase / ALOX5 was used as the immunogen for the 5-Lipoxygenase antibody.
Limitation:
This 5-Lipoxygenase antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P09917