Cyclin E2 Antibody / CCNE2

Western blot: 1:500-1:1000

Optimal dilution of the Cyclin E2 antibody should be determined by the researcher.

'G1/S-specific cyclin-E2' belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [RefSeq]

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide specific to human Cyclin E2 / CCNE2 was used as the immunogen for the Cyclin E2 antibody.

This Cyclin E2 antibody is available for research use only.

Affinity purified

Human

O96020