NSJ Bioreagents

Bcl10 Antibody

Product Code:
 
NSJ-RQ4824
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
GDB-2
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store the Bcl10 antibody at -20°C.
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Western blot testing of human 1) HeLa and 2) Raji cell lysate with Bcl10 antibody. Expected molecular weight: 26-33 kDa.
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Western blot testing of human 1) HeLa and 2) Raji cell lysate with Bcl10 antibody. Expected molecular weight: 26-33 kDa.

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NSJ-RQ4824-100ul100ul£535.00
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Further Information

Application Details :
Western blot: 1:1000-1:2000
Application Note:
Optimal dilution of the Bcl10 antibody should be determined by the researcher.
Description:
Bcl10 contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. It is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. Bcl10 is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human Bcl10 was used as the immunogen for the Bcl10 antibody.
Limitation:
This Bcl10 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
O95999