NSJ Bioreagents

TRAIL R2 Antibody / DR5

Product Code:
 
NSJ-RQ4711
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
ABFC-20
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store the DR5 antibody at -20°C.
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Western blot testing of human HeLa cell lysate with DR5 antibody. Expected molecular weight: ~40 kDa (mature form) and ~48 kDa (precursor). This protein may also be visualized at ~60 kDa.
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Western blot testing of human HeLa cell lysate with DR5 antibody. Expected molecular weight: ~40 kDa (mature form) and ~48 kDa (precursor). This protein may also be visualized at ~60 kDa.

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NSJ-RQ4711-100ul100ul£535.00
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Further Information

Application Details :
Western blot: 1:1000-1:5000
Application Note:
Optimal dilution of the DR5 antibody should be determined by the researcher.
Description:
The protein encoded by the TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. Death receptor 5 can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human DR5 / TNFRSF10B was used as the immunogen for the DR5 antibody.
Limitation:
This DR5 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
O14763