Nordic MuBio

Rabbit anti Human Protein Phosphatase 2 A/B gamma

Product Code:
 
EXA-P180P
Product Group:
 
Primary Antibodies
Supplier:
 
Nordic MuBio
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Bovine (Cattle)
  • Human
  • Mouse
  • Rat
Shipping:
 
Ship at ambient temperature freeze upon arrival
Storage:
 
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
 

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CodeSizePrice
EXA-P180P100 ug£316.00
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Further Information

Applications Description:
Detects PP2A/B isoforms by Western blot analysis. Detects a 56 kDa band in whole rat brain homogenates. Optimal concentration should be evaluated by serial dilutions.
Background:
Protein phosphatase 2A (PP2A) is a hetertrimeric enzyme consisting of a catalytic subunits (C), a structural subunit (A) and a variable regulatory subunit (B). The B subunit family is made up of the , and isoforms. The PP2A/B isoform appears to only be detectable in the brain where it has been speculated that it cytoskeletal substrates. The RNA which produces the PP2A/B is developmentally regulated and increases sharply after birth. It has also been suggested that it may be important in the establishment and maintenance of neuronal connections.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Signal Transduction
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
Antibody raised against synthetic peptide corresponding to amino acids 53 to 66 of the mammalian protein phosphatase 2 A/B conjugated to KLH.
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Ammonium Sulfate Precipitation
Synonyms:
Protein Phosphatase 2 A/B?2
UniProt:
Q13362 (Human) P97888 (Rat) Q8BG02 (Mouse)

References

1. Strack, S., et al. Brain protein phosphatase 2A: Developmental regulation and distinct cellular and subcellular localization by B subunits. J. Comp. Neurol. 1998, 392, 515-527