Nordic MuBio

Mouse anti Human myc

Product Code:
 
EXA-N110M
Product Group:
 
Primary Antibodies
Supplier:
 
Nordic MuBio
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2a
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
8
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Shipping:
 
Room Temperature
Storage:
 
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
 

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CodeSizePrice
EXA-N110M100 ug£316.00
Quantity:
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  • Further Information
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Further Information

Applications Description:
Applications: Western Blot, Immunoprecipitation (Both with and without SDS)
Background:
Human c-myc belongs to a family of 5 myc oncogenes. Amplification of c-myc has been found in several tpes of human tumors including breast and colon carcinomas. Induction of c-myc in cells grown in the appropriate growth factors or co-expression with survival genes, such as bcl-2 causes cell proliferation. In the abscence of these factors, c-myc expression causes cell death. c-myc gene gives rise to at least two nuclear phosphoproteins of 64kDa and 67kDa.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Signal Transduction
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant full-length human c-Myc protein and mouse myeloma cells.
Product Form:
Unconjugated
Product Stability:
Antibodies are stable for one year from purchase if stored frozen
Purification Method:
Protein A/G Chromatography
Source:
Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant full-length human c-Myc protein and mouse myeloma cells.
Synonyms:
cmyc; Myc proto-oncogene protein; transcription factor p64
UniProt:
P01106 (Human) P01108 (Mouse) P09416 (Rat)

References

1) K. Alitala et. al. (1983) Proc. Natl. Acad. Sci., 80: 1707-1711

2)H. Person et.al. (1984) Science 225 687-693