Nordic MuBio

Mouse anti Human p107

Product Code:
 
EXA-N100M
Product Group:
 
Primary Antibodies
Supplier:
 
Nordic MuBio
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
KAB6
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Room Temperature
Storage:
 
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
 

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CodeSizePrice
EXA-N100M100 ug£316.00
Quantity:
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Further Information

Applications Description:
Applications: Western Blots at 1:1000
Background:
The immunogen used was a recombinant protein to the N terminus of p107. p107 is related both in structure and function to the retinoblastoma tumor suppressor protein and p130 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p107 converts E2F transcription factors from transcriptional activators to transcriptional repressors. KAB6 recognizes both the phosphorylated and unphosphorylated forms of p107 at a MW of 107kDa.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Cell Cycle
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blot
Immunogen:
Recombinant GST protein to the N terminus of p107
Product:
KAB6 recognizes both the phosphorylated and unphosphorylated forms of p107 at a MW of 107kDa.
Product Form:
Unconjugated
Product Stability:
Antibodies are stable for one year from purchase if stored frozen
Purification Method:
Protein A/G Chromatography
Source:
The immunogen used to immunize the mice was a recombinant GST protein coupled to the N-terminus of p107.
Synonyms:
p107; Retinoblastoma-like protein 1; PRB1; 107 kda retinoblastoma-associated protein
UniProt:
P28749 (Human) Q64701 (Mouse)