Nordic MuBio

Rabbit anti Rat BAG-5

Product Code:
 
EXA-X1596P
Product Group:
 
Primary Antibodies
Supplier:
 
Nordic MuBio
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Rat
Shipping:
 
Ship at ambient temperature freeze upon arrival
Storage:
 
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
 

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CodeSizePrice
EXA-X1596P100 ug£316.00
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Further Information

Applications Description:
Anibody can be used for Western blotting (5-10 ?g/ml). Optimal concentration should be evaluated by serial dilutions.
Background:
It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70?s anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAG heterodimerization.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Apoptosis
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
Synthetic peptide derived from the human BAG-5 protein.
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Ammonium Sulfate Precipitation
UniProt:
Q9UL15 (Human)

References

1. Takayama,S., et al. 'An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.' J. Biol. Chem. 1999, 274: 781-786