Nordic MuBio

Sheep anti bcl-2

Product Code:
 
EXA-A105P
Product Group:
 
Primary Antibodies
Supplier:
 
Nordic MuBio
Host Type:
 
Sheep
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Canine (dog)
  • Human
  • Rat
Shipping:
 
room temperature
Storage:
 
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
 

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CodeSizePrice
EXA-A105P250 ug£316.00
Quantity:
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This product comes from: Netherlands.
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Further Information

Applications Description:
Applications: Western Blots at 1:5,000, Immunoprecipitation ? Empirical, Immunofluorescence 1:5000.
Background:
Human hematopoetic malignancies are often characterized by gene rearrangements that deregulate gene expression. Antibodies to human bcl-2 (B cell leukemia/lymphoma 2) are directed against the gene isolated at the chromosomal breakpoint t(14;18) Bcl-2 which suppress programmed cell death (apoptosis) and appears to be modulated by association with bax, a cell death promoter.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Field of Interest:
Apoptosis
Formulation:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Functional Analysis:
Western Blotting
Immunogen:
Full length recombinant bcl-2 protein
Product:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Purification Method:
Ammonium Sulfate Precipitation
Source:
Sheep were immunized with full length recombinant bcl-2 protein
Synonyms:
hbcl2, sheep anti human bcl 2, bcl-2
UniProt:
P10415

References

1. Chida, Y., et al. 'The hepatic sympathetic nerve plays a critical role in preventing Fas induced liver injury in mice.' Gut 2005, 54, 994-1002 (Product specific)