Ropivacaine
Product Code:
CDX-R0124
CDX-R0124
Regulatory Status:
RUO
RUO
Shipping:
Ambient
Ambient
Storage:
-20°C
-20°C
No additional charges, what you see is what you pay! *
Code | Size | Price |
---|
CDX-R0124-M050 | 50 mg | £121.00 |
Quantity:
CDX-R0124-M250 | 250 mg | £450.00 |
Quantity:
Prices exclude any Taxes / VAT
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* Rare exceptions are clearly labelled (only 0.14% of items!).
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
- Further Information
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Further Information
Alternate Names/Synonyms:
(S)-Ropivacaine; (2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide
Appearance:
White to off-white powder.
CAS:
84057-95-4
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H302
InChi:
InChI=1S/C17H26N2O/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20)
InChiKey:
ZKMNUMMKYBVTFN-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 84057-95-4. Formula: C17H26N2O. MW: 274.4. Synthetic. Ropivacaine is a long-acting amide local anaesthetic agent. Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. It is a pure S(-)enantiomer and less lipophilic than racemic sodium channel blockers, such as bupivacaine and is less likely to penetrate large myelinated motor fibres, resulting in a relatively reduced motor blockade. Thus, ropivacaine has a greater degree of motor sensory differentiation, which could be useful when motor blockade is undesirable. The reduced lipophilicity is also associated with decreased potential for central nervous system toxicity and cardiotoxicity.
MDL:
MFCD00864425
Molecular Formula:
C17H26N2O
Molecular Weight:
274.4
Package Type:
Vial
Precautions:
P301+P312+P330
Product Description:
Ropivacaine is a long-acting amide local anaesthetic agent. Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. It is a pure S(-)enantiomer and less lipophilic than racemic sodium channel blockers, such as bupivacaine and is less likely to penetrate large myelinated motor fibres, resulting in a relatively reduced motor blockade. Thus, ropivacaine has a greater degree of motor sensory differentiation, which could be useful when motor blockade is undesirable. The reduced lipophilicity is also associated with decreased potential for central nervous system toxicity and cardiotoxicity.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
CC1=CC=CC(C)=C1NC(C2CCCCN2CCC)=O
Solubility Chemicals:
Soluble in chloroform or acentonitrile. Slightly soluble in DMSO or methanol.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
Documents
References
(1) R.D. Wang, et al.; Exp. Opin. Pharmacother. 2, 2051 (2001) (Review) | (2) T.G. Hansen; Exp. Rev. Neurother. 4, 781 (2004) (Review) | (3) G. Kuthiala & G. Chaudhary; Indian J. Anaesth. 55, 104 (2011) (Review)