ProSci

RUNX3 Antibody [RNX864]

Product Code:
 
PSI-33-059
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
RNX864
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
blue ice
Storage:
 
Aliquot and Store at -20C. Avoid freez-thaw cycles.
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Western blot testing of human samples with RUNX3 antibody at 2 ug/ml.
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Western blot testing of human samples with RUNX3 antibody at 2 ug/ml.

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CodeSizePrice
PSI-33-059-100ug100ug£662.00
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Further Information

Additional Names:
Runt-related transcription factor 3, Acute myeloid leukemia 2 protein, Core-binding factor subunit alpha-3, CBF-alpha-3, Oncogene AML-2, Polyomavirus enhancer-binding protein 2 alpha C subunit, PEA2-alpha C, PEBP2-alpha C, SL3-3 enhancer factor 1 alpha C subunit, SL3/AKV core-binding factor alpha C subunit, RUNX3, AML2, CBFA3, PEBP2A3
Application Note:
Western blot: 2-4 ug/ml

Provided assay concentrations are suggestions only, RUNX3 antibody titration may be required for optimal results.
Background:
The Runt family of transcription factors is involved in both normal cell development and carcinogenesis. Runt-related transcription factor 3 has been shown to be a tumor suppressor. Hypermethylation and mislocalization of the protein to the cytoplasm leads to low levels of RUNX3 and increased proliferation of breast and gastric tumor cells.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A RUNX3 recombinant protein fragment was used as the immunogen for this antibody.
NCBI Gene ID #:
864
NCBI Official Name:
Runt-related transcription factor 3
NCBI Official Symbol:
RUNX3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G Affinity Chromatography
Research Area:
Other
Swissprot #:
Q13761
User NOte:
Optimal dilutions for each application to be determined by the researcher