ProSci

CD37 Antibody [IPO-24]

Product Code:
 
PSI-33-505
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2b, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
IPO-24
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Functional Study
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
 
blue ice
Storage:
 
Aliquot and Store at -20C. Avoid freez-thaw cycles.
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SDS-PAGE Analysis of Purified, BSA-Free CD37 Antibody (clone IPO-24). Confirmation of Integrity and Purity of the Antibody.

SDS-PAGE Analysis of Purified, BSA-Free CD37 Antibody (clone IPO-24). Confirmation of Integrity and Purity of the Antibody.

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PSI-33-505-100ug100ug£765.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
Leukocyte antigen CD37, Tetraspanin-26, Tspan-26, CD37, CD37, TSPAN26
Application Note:
Functional Activity (Order SAF formulation)

Flow Cytometry: 0.5-1 ug/million cells in 0.1ml

Immunofluorescence: 0.5-1 ug/ml

Optimal dilution of the CD37 antibody should be determined by the researcher.
Background:
Recognizes a protein of 33-55kDa, identified as CD37 (Workshop V; Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL).
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
NCBI Gene ID #:
951
NCBI Official Name:
CD37 molecule
NCBI Official Symbol:
CD37
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Immunology
Swissprot #:
P11049
User NOte:
Optimal dilutions for each application to be determined by the researcher