ProSci

CD8beta Antibody [EP42] (PE)

Product Code:
 
PSI-99-249
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2a
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[EP42]
Regulatory Status:
 
RUO
Target Species:
 
Chicken (Gallus)
Applications:
  • Blocking
  • Immunoprecipitation (IP)
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
1 / 1
Chicken peripheral blood mononuclear cells were stained with Mouse Anti-Chicken CD8b-PE (Cat. No. 99-249) and Mouse Anti-Chicken CD4-FITC .
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Chicken peripheral blood mononuclear cells were stained with Mouse Anti-Chicken CD8b-PE (Cat. No. 99-249) and Mouse Anti-Chicken CD4-FITC .

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CodeSizePrice
PSI-99-249-0.1mg0.1mg£560.00
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Further Information

Application Note:
CD8beta Antibody [EP42] for use in flow cytometry assays.
Background:
In the chicken, the CD8 molecule is present in two forms - (i) a homodimer of two alpha chains and (ii) a heterodimer of an alpha chain and a beta chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8alpha- and CD8beta-chains, a relatively large proportion of the CD8+ TCR-gammadelta cells in the spleens of embryos and young chicks express only the alpha-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCR-gammadelta CD8alphabeta cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. The monoclonal antibody EP42 recognizes the CD8beta chain.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
0.1 mg/mL
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Chicken splenocytes
NCBI Gene ID #:
396175
NCBI Official Name:
CD8b molecule
NCBI Official Symbol:
CD8B
NCBI Organism:
Gallus gallus
Physical State:
Liquid
Research Area:
Cancer,Immunology
SPECIFICITY:
CD8beta
User NOte:
Optimal dilutions for each application to be determined by the researcher.