ProSci

CLEC1 Antibody

Product Code:
 
PSI-33-024
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
blue ice
Storage:
 
Aliquot and Store at -20C. Avoid freez-thaw cycles.
1 / 1
Western blot testing of human samples with CLEC1 antibody at 2ug/ml.
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Western blot testing of human samples with CLEC1 antibody at 2ug/ml.

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CodeSizePrice
PSI-33-024-100ug100ug£662.00
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Further Information

Application Note:
Western blot: 2-5 ug/ml

Provided assay concentrations are suggestions only, CLEC1 antibody titration may be required for optimal results.
Background:
CLEC1 is a C-type lectin receptor and part of the ?Dectin-1 cluster? subfamily which also includes Dectin-1, LOX-1, CLEC-2, MICL, CLEC12B, and CLEC9A. Similar to other family members, CLEC1 displays N-liked glycosylation and dimerization characteristics, and is found on dendritic cells, monocytes and granulocytes. However, unlike other family members, CLEC1 expression level is upregulated by IL-10 and TGFb, but not by pro-inflammatory stimuli, and it is expressed on endothelial cells. Enhanced expression at allograft sites suggests CLEC1 may have an immune-regulatory function and may support allograft tolerance.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant protein fragment from the N-terminal portin of human CLEC1 was used as the immunogen for this antibody.
NCBI Gene ID #:
51267
NCBI Official Name:
C-type lectin domain family 1 member A
NCBI Official Symbol:
CLEC1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein A purified antibody
Research Area:
Immunology, Signal Transduction
Swissprot #:
Q8NC01
User NOte:
Optimal dilutions for each application to be determined by the researcher