ProSci

MCAM Antibody [C264] (FITC)

Product Code:
 
PSI-99-303
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2b
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[C264]
Regulatory Status:
 
RUO
Target Species:
  • Chicken (Gallus)
  • Turkey
Applications:
  • Blocking
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunoprecipitation (IP)
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
1 / 1
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PSI-99-303-0.5mg0.5mg£729.00
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Further Information

Additional Names:
CD146, HEMCAM, melanoma cell adhesion molecule
Application Note:
MCAM Antibody [C264] for use in flow cytometry and immunocytochemistry assays.
Background:
Chicken MCAM, a member of the immunoglobulin superfamily of cell surface receptors, consists of the V-V-C2-C2-C2 Ig domains. It is a single chain glycoprotein with three mRNA splice variants. One has a short cytoplasmic tail, another has a long tail, and the third seems to lack transmembrane and cytoplasmic regions. It is highly homologous to gicerin, a molecule involved in neurite outgrowth and Wilm?s kidney tumor progression in the chicken, and to the human melanoma progression molecule MUC18. Chicken MCAM is expressed by c-kit+ hematopoietic progenitor cells in embryonic bone marrow, thymocytes, and capillary endothelial cells. MCAM-expressing cells sorted from bone marrow are enriched in progenitors capable of differentiating into T cells when transferred into the appropriate thymic microenvironment. MCAM has been proposed to be involved in cellular adhesion and homing processes.
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Mixture of E15 and E16 thymocytes from H.B15, H.B19, and H.B21 chicken embryos
NCBI Gene ID #:
448832
NCBI Official Name:
melanoma cell adhesion molecule
NCBI Official Symbol:
MCAM
NCBI Organism:
Gallus gallus
Physical State:
Liquid
Research Area:
Cancer,Immunology,Signal Transduction
SPECIFICITY:
MCAM
User NOte:
Optimal dilutions for each application to be determined by the researcher.