ProSci

CD54 Antibody [15.2] (PE)

Product Code:
 
PSI-99-391
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[15.2]
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
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Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD54-PE (Cat. No. 99-391).
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Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD54-PE (Cat. No. 99-391).

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PSI-99-391-100tests100tests£560.00
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Further Information

Additional Names:
ICAM-1, intracellular adhesion molecule-1, Ly-47
Application Note:
CD54 Antibody [15.2] for use in flow cytometry assays.
Background:
CD54, also known as intercellular cell adhesion molecule-1 (ICAM-1), is a 90 kDa type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It exhibits a wide tissue distribution being expressed on both hematopoietic and non-hematopoietic cells. ICAM-1 expression on leukocytes is low but is rapidly upregulated upon activation. Expression on endothelium and other non-hematopoietic cells is strongly upregulated by inflammatory mediators. The ligands of CD54 are CD11a/LFA-1alpha and CD11b/Mac-1alpha. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels particularly in areas of inflammation. CD54 on antigen-presenting cells (APC) contributes to antigen-specific T cell activation presumably by enhancing interactions between T cells and APC.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
Lot specific
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Rheumatoid synovial cells and human monocytes
NCBI Gene ID #:
3383
NCBI Official Name:
Intercellular adhesion molecule 1
NCBI Official Symbol:
ICAM1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P05362
Research Area:
Immunology,Signal Transduction
SPECIFICITY:
CD54
Swissprot #:
P05362
User NOte:
Optimal dilutions for each application to be determined by the researcher.