ProSci

CD43 Antibody [DF-T1]

Product Code:
 
PSI-99-523
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[DF-T1]
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Blocking
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunoprecipitation (IP)
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
1 / 1
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PSI-99-523-0.1mg0.1mg£373.00
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Further Information

Additional Names:
gpL115, leukocyte sialoglycoprotein
Application Note:
CD43 Antibody [DF-T1] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, and adhesion assays.
Background:
CD43, a member of the sialomucin family of cell surface receptors, is a 95-135 kDa type I transmembrane glycoprotein whose variability in molecular weight is dependent upon the nature of the extracellular O-glycans. It is the major sialoglycoprotein on thymocytes, T cells, and neutrophils. It is also present on activated B cells, plasma cells, NK cells, granulocytes, monocytes, macrophages, platelets, and bone marrow hematopoietic stem cells. CD43, which binds to ICAM-1 (CD54), appears to function as an anti-adhesion molecule, inhibiting T cell interactions including T cell killing, and by increasing the threshold for T cell activation.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
KG-1 cells
NCBI Gene ID #:
6693
NCBI Official Name:
sialophorin
NCBI Official Symbol:
SPN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P16150
Research Area:
Immunology
SPECIFICITY:
CD43
Swissprot #:
P16150
User NOte:
Optimal dilutions for each application to be determined by the researcher.