ProSci

CD40 Antibody [1C10] (PE-Cy5)

Product Code:
 
PSI-98-767
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rat
Antibody Isotype:
 
IgG2a
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[1C10]
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
1 / 1
BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD40-SPRD (Cat. No. 98-767).
❮❯

BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD40-SPRD (Cat. No. 98-767).

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PSI-98-767-0.1mg0.1mg£657.00
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Further Information

Additional Names:
TNFRSF5, Bp50
Application Note:
CD40 Antibody [1C10] for use in flow cytometry assays.
Background:
CD40 is a type I cell surface protein belonging to the tumor necrosis factor superfamily of cell surface receptors. In mice it is expressed on B lineage cells, follicular dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zone of secondary lymphoid organs. CD40 first becomes detectable on a subset of small pre-B II cells in bone marrow with the levels of CD40 expression increasing thereafter during B cell maturation. Immature B cells (IgM+IgDloB220lo) express intermediate levels of CD40, whereas mature B cells (IgM+IgDhiB220hi) express high levels. CD40 has a central role in B cell growth and differentiation, and signaling through CD40 in combination with IL-4 reportedly induces immunoglobulin isotype switching and secretion of IgE. The agonistic 1C10 antibody closely resembles gp39/CD40 ligand in its ability to stimulate proliferation of small, resting B lymphocytes in the absence of other cofactors.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
0.1 mg/mL
Conjugate:
PE-Cy5
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
sCD40
NCBI Gene ID #:
21939
NCBI Official Name:
CD40 antigen
NCBI Official Symbol:
Cd40
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P27512
Research Area:
Cancer,Immunology,Innate Immunity
SPECIFICITY:
CD40
Swissprot #:
P27512
User NOte:
Optimal dilutions for each application to be determined by the researcher.