ProSci

CD158e1 Antibody [DX9] (APC)

Product Code:
 
PSI-99-610
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[DX9]
Regulatory Status:
 
RUO
Target Species:
  • Baboon
  • Human
Application:
 
Flow Cytometry
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
1 / 1
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PSI-99-610-100tests100tests£597.00
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Further Information

Additional Names:
NKB1, p70, KIR, 3DL1, KIR3DL1, KIR3D, NKAT3
Application Note:
CD158e1 Antibody [DX9] for use in flow cytometry assays.
Background:
CD158e1 is a 70 kDa transmembrane glycoprotein and a killer cell immunoglobulin (Ig)-like receptor (KIR) that is expressed on a subset of natural killer cells and T cells. The monoclonal antibody DX9 is expressed on a subset of CD3-, CD56+ NK cells isolated from peripheral blood at varying levels (<0.1% to 61%) among individuals but not on thymocytes, B lymphocytes, granulocytes, or monocytes. Interactions with CD158e1 and certain MHC HLA-B antigens on a target cell inhibits cytotoxicity, possibly preventing target cell lysis and death. KIR and MHC class I interactions may regulate NK and T cell response to antigen stimulation.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
Lot specific
Conjugate:
APC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Human NK clone VL186-1 (CD3-, CD16+, CD56+)
NCBI Gene ID #:
3811
NCBI Official Name:
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
NCBI Official Symbol:
KIR3DL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P43629
Research Area:
Immunology
SPECIFICITY:
CD158e1
Swissprot #:
P43629
User NOte:
Optimal dilutions for each application to be determined by the researcher.