ProSci

Bcl-2 Antibody [10C4]

Product Code:
 
PSI-99-624
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[10C4]
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Flow Cytometry
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
1 / 1
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PSI-99-624-0.1mg0.1mg£505.00
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Further Information

Additional Names:
B cell leukemia 2
Application Note:
Bcl-2 Antibody [10C4] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and immunoprecipitation assays.
Background:
Bcl-2 is a 26 kDa member of the family of proteins involved in regulation of programmed cell death, or apoptosis. It is expressed in a variety of both normal and neoplastic tissues and appears to be membrane-bound since it is detectable in crude membrane and nuclear fractions, but not in the soluble fraction of cell lysates. Overexpression of Bcl-2 can prevent apoptosis, while formation of heterodimers with Bax, another Bcl-2-related protein, inhibits Bcl-2?s ability to promote cell survival.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Murine Bcl-2 peptide (a.a. 61-76)
NCBI Gene ID #:
12043/24224
NCBI Official Name:
B cell leukemia/lymphoma 2
NCBI Official Symbol:
Bcl2
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P10417
Research Area:
Cancer,Obesity,Signal Transduction
SPECIFICITY:
Bcl-2
Swissprot #:
P10417
User NOte:
Optimal dilutions for each application to be determined by the researcher.