Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.
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United States.
Typical lead time:
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Further Information
ILPIP Antibody: PAPK, ILPIP, ILPIPA, ALS2CR2, CALS-21, PRO1038, STE20-related kinase adapter protein beta, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein, STRAD beta
Western blot: 5-10 ug/ml
Provided assay concentrations are suggestions only, Als2Cr2 antibody titration may be required for optimal results. This antibody will detect the 418 (ILPIP alpha) and 280 (ILPIP beta) amino acid isoforms.
Als2Cr2, also called STE20-related kinase adapter protein beta (STRAD beta) and ILPIP, is a serine/threonine protein kinase encoded by the STRADB gene, discovered as an XIAP interacting protein. It is a mediator of the XIAP/TAK1 activation of the JNK1 pathway, an apoptosis inhibition mechanism independent of XIAP inhibition of caspases. Alone, it only moderately activates JNKs, but its interaction with XIAP/TAK1 induces a much stronger activation of JNK1, protecting against Caspase 1- or Fas-induced apoptosis.
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
0.5 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
A recombinant protein fragment from the interior region of human Als2Cr2 was used as the immunogen for this antibody.
55437
STE20-related kinase adaptor beta
STRADB
Homo sapiens
Liquid
Protein A affinity chromatography
Apoptosis
Q9C0K7
Optimal dilutions for each application to be determined by the researcher